Diabetes complications

Residential Address Amplifies Health Disparities and Risk of Infection in Individuals With Diabetic Foot Ulcers

Diabetes CarePublished Retrospective cohort study

Authors' conclusion

We found significant differences in neighborhood characteristics driving a higher risk for DFU infection in comparisons with the grouping of individuals with diabetes overall, including increased risk for individuals with Hispanic and/or foreign-born immigration status. These data strongly support the need to incorporate SDOH, particularly ethnic and immigration status, into triage algorithms for DFU risk stratification to prevent severe diabetic foot complications and move beyond biologic-only determinants of health.

Study context

Population
Individuals with diabetes seen between 2013 and 2017 (EHR, 4.3 million people overall); 8,351 developed DFU144,564 with diabetes
Participants
2,252 vs 144,564
Exposure
Individuals with DFU infection vs population with diabetes overall
  • DFU infectionn = 2,252
  • Diabetes overalln = 144,564reference
Outcome
DFU infection, associated with social determinants of health (SDOH)
Methodological detailselectronic health record data, geolocated neighborhood data
  • Electronic health record data
  • Geolocated neighborhood data

Main finding

As reported in the abstract

Association of neighborhood Hispanic and/or foreign-born concentration with DFU infection (multiple logistic regression)

Odds ratio

1.11

P = 0.015

Observational data: associations, not effects.

Original publication

Residential Address Amplifies Health Disparities and Risk of Infection in Individuals With Diabetic Foot Ulcers. Diabetes Care. Published 19 January 2024. doi:10.2337/dc23-1787

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