The Physiology Of the WEight Reduced State (POWERS) study: design and rationale for assessment of food intake, physical activity and other behavioral constructs
Study context
- Population
- Healthy adults aged 25-<60 years with BMI 30-<40 kg/m², after a behavioral weight loss program
- Participants
- 205 adults
Methodological detailsmulticentre, serial assessments, one of five-part series on study design, Up to four serial assessments: before weight loss; after ≥7% weight loss; and four and 12 months later
- Multicentre
- Serial assessments
- One of five-part series on study design
- Up to four serial assessments: before weight loss; after ≥7% weight loss; and four and 12 months later
Main finding
As reported in the abstract
- Energy intake and eating-related behaviors measured with standardized laboratory meals
- Behavioral and neurocognitive eating factors assessed via computer-based tasks and self-report questionnaires; functional and structural neuroimaging identify underlying neural circuitry
- Psychological factors related to weight regulation assessed via self-report questionnaires
- Free-living physical activity and sleep measured via accelerometry, polysomnography and self-report questionnaires
Original publication
The Physiology Of the WEight Reduced State (POWERS) study: design and rationale for assessment of food intake, physical activity and other behavioral constructs. Int J Obes (Lond). Published 9 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →