The Osteoporotic Fractures in Men study (MrOS): a 25-yr landmark study of skeletal health in older men
Study context
- Population
- Community-dwelling, ambulatory US men aged ≥65 yr recruited at 6 US academic clinical centers in 2000–2002, followed through November 2024
- Participants
- 5,994 participants
- Outcome
- Overview of MrOS findings
- Follow-up
- 25 yr
Methodological detailsmulticentre, 25-yr follow-up, Serum, urine and DNA collected at clinic visits, Mail/phone contact every 4 mo for falls, fractures, deaths; fractures confirmed by imaging reports, 5 major clinic visits; ancillary sleep study with 2 additional visits
- Multicentre
- 25-yr follow-up
- Serum, urine and DNA collected at clinic visits
- Mail/phone contact every 4 mo for falls, fractures, deaths; fractures confirmed by imaging reports
- 5 major clinic visits; ancillary sleep study with 2 additional visits
Main finding
As reported in the abstract
Complete follow-up among active surviving participants
95%
Observational data: associations, not effects.
Original publication
The Osteoporotic Fractures in Men study (MrOS): a 25-yr landmark study of skeletal health in older men. J Bone Miner Res. Published 5 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →