Leg power and velocity predict the risk of major osteoporotic fractures (MOF): the Osteoporotic Fractures in Men (MrOS) study
Authors' conclusion
In older men, peak leg power and velocity, but not force, predicted MOF risk independent of FN BMD.
Study context
- Population
- Older men (median age 84 yr), Osteoporotic Fractures in Men (MrOS) study136 incident MOF
- Participants
- 1,841 men
- Exposure
- Jump test power measures; excluded from jump tests as lowest group
- Lowestn = 599
- Outcome
- Incident major osteoporotic fractures (MOF), confirmed by medical record
- Follow-up
- 5 yr
Methodological detailsmultiply adjusted Cox proportional hazards models
- Multiply adjusted Cox proportional hazards models
Main finding
As reported in the abstract
MOF per one SD increment of jump test measure (multiply adjusted) · 5 yr
Hazard ratio (95% CI)
Peak power/kg body weight (per one SD increment)
0.71(0.54–0.92)
Velocity at peak power (per one SD increment)
0.76(0.59–0.98)
Per one SD increment, as printed
Observational data: associations, not effects.
Further findings
MOF across quartiles of power and velocity
- Significant trend of decreasing MOF with increasing power and velocity
MOF across quartiles of force at peak power
- Only the highest quartile of force was significantly associated with lower MOF risk; not significant after adjusting for femoral neck (FN) bone mineral density (BMD)
Original publication
Leg power and velocity predict the risk of major osteoporotic fractures (MOF): the Osteoporotic Fractures in Men (MrOS) study. J Bone Miner Res. Published 4 February 2026. doi:10.
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