Type 1 diabetes

The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children With Type 1 Diabetes

Diabetes CarePublished Subgroup analysis of a randomised controlled trial

Authors' conclusion

The BP improves glycemic control in both Whites and Minorities and offers promise in decreasing health care disparities.

Study context

Population
Adults and children with T1D; subgroups: non-Hispanic White ("Whites", n = 240) and Black, Hispanic and other ("Minorities", n = 84)161 adults · 165 children
Comparison
iLet bionic pancreas vs standard of care, by race/ethnicity
Methodological detailsmulticenter, randomized controlled
  • Multicenter
  • Randomized controlled

Primary result

As reported in the abstract

HbA1c, mean baseline-adjusted difference, by subgroup · 13 weeks
BP vs SCMean baseline-adjusted difference, % (95% CI)P value
Whites (n = 240); −4.9 mmol/mol (−6.6 to −3.1)
−0.45(−0.61 to −0.29)
P < 0.001
Minorities (n = 84); −6.0 mmol/mol (−9.2 to −2.8)
−0.53(−0.83 to −0.24)
P < 0.001

Further findings

OutcomeMean baseline-adjusted difference (%) (95% CI)P value
TIR, mean baseline-adjusted difference, by subgroupBPvs SCWhites10 (7–12)P < 0.001
TIR, mean baseline-adjusted difference, by subgroupBPvs SCMinorities14 (10–18)P < 0.001

Original publication

The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children With Type 1 Diabetes. Diabetes Care. Published 31 March 2023. doi:10.2337/dc22-1478

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