Type 2 & other diabetes

The influence of diabetes and hyperglycemia on short and long-term mortality after the first-ever known COVID-19 infection

Diabetes Res Clin PractPublished Cohort study

Authors' conclusion

Diabetes associated with other comorbidities had the highest risks of all-cause mortality in the short and long-term, hyperglycemia was a long-term marker of poor prognostic after COVID-19 infection.

Study context

Population
Patients with first-ever known COVID-19 infection; 30.1 % had diabetes
Participants
455 patients
Exposure
Diabetes (alone or with comorbidities) and hyperglycemia without diabetes vs reference, for post-COVID-19 mortality
Outcome
All-cause mortality
Follow-up
1-week to 1-year

Main finding

As reported in the abstract

All-cause mortality after COVID-19
Hazard ratio (95% CI)
Diabetes only7 days
6.24(1.03–37.77)
Diabetes with hypertension and CKD1-week
7.98(1.03–61.70)
Diabetes with hypertension and CKD1-year
2.27(1.03–4.99)
FBG ≥ 110 mg/dl (without diabetes)1-year
2.80(1.10–7.22)
FBG ≥ 126 mg/dl (without diabetes)1-year
2.54(1.10–5.88)

Observational data: associations, not effects.

Original publication

The influence of diabetes and hyperglycemia on short and long-term mortality after the first-ever known COVID-19 infection. Diabetes Res Clin Pract. Published 18 March 2025. doi:10.1016/j.diabres.2025.112100

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