Clinical and biochemical profile of individuals with renal glucosuria: A matched cohort study
Authors' conclusion
In young adults, renal glucosuria was associated with higher haematocrit and lower uric acid, with no other cardiometabolic differences from controls.
Study context
- Population
- Adults in Maccabi Healthcare Services (Israeli health maintenance organization) with ≥2 urine dipstick tests ≥3 months apart within 10 years; excluded prediabetes or DM, SGLT2i use and pregnancy; mean age 36.9 ± 12 years, 70% female, mean BMI 24.1 ± 4.1 kg/m²matched cohort
- Participants
- 880 adults
- Exposure
- Renal glucosuria vs matched controls
- Renal glucosurian = 220
- Controlsn = 660reference
- Outcome
- Clinical and laboratory characteristics
Methodological detailsmatched 1:3 by age, sex, weight and BMI, univariate and multivariate logistic regression
- Matched 1:3 by age, sex, weight and BMI
- Univariate and multivariate logistic regression
Main finding
As reported in the abstract
Renal glucosuria vs ControlsAdjusted odds ratio (95% CI)
Higher haematocrit
1.10(1.04–1.16)
Lower blood uric acid
0.70(0.58–0.85)
Observational data: associations, not effects.
Original publication
Clinical and biochemical profile of individuals with renal glucosuria: A matched cohort study. Diabetes Obes Metab. Published 17 March 2025. doi:10.
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