The Impact of Hypoglycaemia on Quality of Life in Adults With Type 1 Diabetes Using Contemporary Diabetes Technologies: A US National Survey
Authors' conclusion
Hypoglycaemia continues to adversely affect multiple related quality-of-life domains despite using contemporary diabetes technologies.
Study context
- Population
- US adults aged ≥18 years with T1D using continuous glucose monitoring (CGM) or HCL, recruited through the T1D Exchange; mean age 47 years, 53% female23% CGM only, 77% HCL
- Participants
- 796 adults
- Exposure
- HCL users vs CGM-only users
- Outcome
- Hypoglycaemia-specific quality of life by the 12-item Hypoglycaemia Impact Profile (HIP-12) across 12 life domains
Methodological detailsnational survey
- National survey
Main finding
As reported in the abstract
Hypoglycaemia impact on life domains (HIP-12)
≥1 life domain negatively affected by hypoglycaemia
96%
Negative impacts across ≥10 of 12 domains
31%
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Hypoglycaemia-related negative impact by domain, HCL vs CGM-onlyHCL vs CGM-only · leisure activities; greater with HCL | P < 0.001 |
| Hypoglycaemia-related negative impact by domain, HCL vs CGM-onlyHCL vs CGM-only · physical activity/fitness; greater with HCL | P < 0.001 |
| Hypoglycaemia-related negative impact by domain, HCL vs CGM-onlyHCL vs CGM-only · spontaneity; greater with HCL | P = 0.011 |
| Hypoglycaemia-related negative impact by domain, HCL vs CGM-onlyHCL vs CGM-only · sex life; greater with HCL | P = 0.014 |
| Hypoglycaemia-related negative impact by domain, HCL vs CGM-onlyHCL vs CGM-only · work or studies; greater with HCL | P = 0.021 |
Original publication
The Impact of Hypoglycaemia on Quality of Life in Adults With Type 1 Diabetes Using Contemporary Diabetes Technologies: A US National Survey. Diabetes Obes Metab. Published 25 June 2026. doi:10.
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