Type 2 & other diabetes

The impact of diabetes on cancer detection during the prevalence round of a national screening program for colorectal cancer

Diabet MedPublished Register-based cohort study

Authors' conclusion

Despite a lower participation rate, the effect of CRC screening was higher in individuals with diabetes.

Study context

Population
Danish residents aged 50–74 years, prevalence round of national colorectal cancer (CRC) screening program 2014–2017; diabetes prevalence 10% in both groups
Participants
504,673 vs 549,359
Exposure
Invited vs not yet invited to CRC screening, in individuals with and without diabetes
  • Invitedn = 504,673
  • Not yet invitedn = 549,359reference
Outcome
Detection of CRC and disease stage among individuals with and without diabetes
Methodological detailsbased on randomized invitation procedure, national
  • Based on randomized invitation procedure
  • National

Main finding

As reported in the abstract

Detected cancers per 100,000 individuals

With diabetes: not yet invited vs invited

207 to 494 cancers

Without diabetes: not yet invited vs invited

147 to 364 cancers

Observational data: associations, not effects.

Further findings

OutcomeDifference (95% CI)
Screening participation rate among invited, diabetesvs no diabetesLower with diabetes9.1% (8.7%–9.5%)

Original publication

The impact of diabetes on cancer detection during the prevalence round of a national screening program for colorectal cancer. Diabet Med. Published 29 January 2023. doi:10.1111/dme.15043

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