Type 2 & other diabetes

Invasive validation of the Antares algorithm for determining central blood pressure based on upper arm oscillometric pulse waves in patients with type 2 diabetes

BMJ Open Diabetes Res CarePublished Diagnostic accuracy study

Authors' conclusion

The present study suggests that the Antares algorithm incorporated into the custo screen 400 device can estimate cBP with high accuracy turning a conventional oscillometric BP device into a type II device for the non-invasive estimation of cBP, which is applicable in patients with type 2 diabetes. Integration of Antares into commercially available BP devices could facilitate the introduction of cBP into routine clinical practice as a part of disease and risk management.

Study context

Population
Consecutive patients with T2D undergoing elective coronary angiography, November 2017 to September 2020
Participants
119 patients
Comparison
Antares-estimated cBP vs invasively measured cBP
Outcome
Accuracy of Antares-estimated cBP vs invasively measured cBP
Methodological detailsinvasive validation, simultaneous measurement
  • Invasive validation
  • Simultaneous measurement

Performance

As reported in the abstract

Agreement of estimated vs invasive cBP

Mean difference (central systolic BP (cSBP))

1.2 mmHg

±6.3 mmHg

Mean difference (central mean arterial pressure (cMAP))

1.0 mmHg

±4.3 mmHg

Mean difference (central diastolic BP (cDBP))

3.6 mmHg

±5.7 mmHg

Correlation, cSBP
r=0.916
Correlation, cMAP
r=0.882
Correlation, cDBP
r=0.791
All correlations
P < 0.001

Original publication

Invasive validation of the Antares algorithm for determining central blood pressure based on upper arm oscillometric pulse waves in patients with type 2 diabetes. BMJ Open Diabetes Res Care. Published 27 January 2023. doi:10.1136/bmjdrc-2022-003119

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