The impact of a low‐carbohydrate (vs. low‐fat) diet on fat mass loss in African American women is modulated by insulin sensitivity
Authors' conclusion
A low-CHO diet leads to a greater FM loss in African American women with obesity and low SI, likely by minimizing the reduction in EE that follows weight loss.
Study context
- Population
- African American women with obesity
- Participants
- 69 women
- Comparison
- Low-CHO vs low-fat hypocaloric diet
- Primary endpoint
- Change in fat mass (FM)
- Follow-up
- Week 10
Methodological detailscontrolled feeding
- Controlled feeding
Primary result
As reported in the abstract
FM change in women with low SI
Low-CHO
−4.9
mean · SE 0.9 · kg
Low-fat
−2.1
mean · SE 1.0 · kg
P = 0.04
Further findings
| Outcome | Low-CHO | Low-fat | P value |
|---|---|---|---|
| Weight change in women with low SIMean, kg | −6.6 (SE 1.0) | −4.1 (SE 1.4) | P = 0.076 |
| REE change in women with low SILower reduction with low-CHO · mean, kcal/day | −48 (SE 30) | −145 (SE 30) | P = 0.035 |
| TEE change in women with low SILower reduction with low-CHO · mean, kcal/day | 67 (SE 56) | −230 (SE 125) | P = 0.009 |
Original publication
The impact of a low‐carbohydrate (vs. low‐fat) diet on fat mass loss in African American women is modulated by insulin sensitivity. Obesity (Silver Spring). Published 5 January 2025. doi:10.
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