Osteoporosis, bone & mineral

The effect of calcium supplementation on bone calcium balance and calcium and bone metabolism during load carriage in women: a randomized controlled crossover trial

J Bone Miner ResPublished Randomised controlled crossover trial

Authors' conclusion

A 1000 mg calcium supplement before load carriage promotes bone calcium balance and prevents disruptions to bone and calcium homeostasis.

Study context

Population
Women performing two load carriage sessions (12.8 km in 120 min carrying 20 kg)40 completed session 2
Participants
48 women
Comparison
1000 mg calcium vs nothing 60 min before load carriage
Methodological detailsrandomized order
  • Randomized order

Primary result

As reported in the abstract

Calcium isotope ratio (δ44/42Ca) and markers of calcium and bone metabolism
Serum δ44/42Ca did not change with load carriage in Control
p = .617
Serum δ44/42Ca increased in Calcium
p = .003
Ionized calcium (iCa) decreased from pre-exercise to all exercise time-points
p < .001
PTH increased from pre-exercise to 120 min in Control
p < .001
PTH decreased from pre-exercise to all time-points in Calcium
p < .001
βCTX decreased from pre-exercise to 20 to +15 min in Control
p ≤ .004
βCTX decreased from pre-exercise to 0 to +90 min in Calcium
p < .001

Original publication

The effect of calcium supplementation on bone calcium balance and calcium and bone metabolism during load carriage in women: a randomized controlled crossover trial. J Bone Miner Res. Published 13 January 2025. doi:10.1093/jbmr/zjaf004

Composed by AI from the published abstract and checked against it. How Briefs are made →

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