Load carriage exercise increases calcium absorption and retention in healthy young women
Authors' conclusion
The rapid reduction in circulating iCa may be due to a change in the miscible Ca pool, resulting in increased PTH and changes in intestinal absorption and renal Ca handling that support a more positive Ca balance.
Study context
- Population
- Healthy young women (26.4 ± 6.7 yr)crossover
- Participants
- 21 women
- Comparison
- Load carriage exercise vs rest
- Primary endpoint
- Ca kinetics: fractional Ca absorption (FCA), bone Ca deposition (Vo+), resorption (Vo-) and balance (Vbal)
Methodological detailsdual stable Ca isotopes
- Dual stable Ca isotopes
Primary result
As reported in the abstract
Fractional Ca absorption (FCA)
P < 0.05
Further findings
Bone Ca deposition (VO+) · not different
P > 0.05
Urinary Ca · day 1 · lower with EX
P = 0.001
| Outcome | EX | REST | P value |
|---|---|---|---|
| Ca balance (Vbal)Less negative with EX | −61.3 ± 111 mg | −108 ± 23.5 mg | P < 0.05 |
| Bone Ca resorption (VO-)Not different | −636 ± 243 mg | −692 ± 252 mg | P > 0.05 |
- Urinary Ca — Urinary Ca over full 24-h collection did not differ
- P > .05
Circulating ionized Ca (iCa) and parathyroid hormone (PTH) · during each session
- iCa decreased and PTH increased during each EX session; unchanged during REST
- P < 0.001
Original publication
Load carriage exercise increases calcium absorption and retention in healthy young women. J Bone Miner Res. Published 4 January 2024. doi:10. 1093/ jbmr/ zjad003
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