Osteoporosis, bone & mineral

Load carriage exercise increases calcium absorption and retention in healthy young women

J Bone Miner ResPublished Randomised crossover study

Authors' conclusion

The rapid reduction in circulating iCa may be due to a change in the miscible Ca pool, resulting in increased PTH and changes in intestinal absorption and renal Ca handling that support a more positive Ca balance.

Study context

Population
Healthy young women (26.4 ± 6.7 yr)crossover
Participants
21 women
Comparison
Load carriage exercise vs rest
Primary endpoint
Ca kinetics: fractional Ca absorption (FCA), bone Ca deposition (Vo+), resorption (Vo-) and balance (Vbal)
Methodological detailsdual stable Ca isotopes
  • Dual stable Ca isotopes

Primary result

As reported in the abstract

Fractional Ca absorption (FCA)

P < 0.05

Further findings

Bone Ca deposition (VO+) · not different

P > 0.05

Urinary Ca · day 1 · lower with EX

P = 0.001

OutcomeEXRESTP value
Ca balance (Vbal)Less negative with EX−61.3 ± 111 mg−108 ± 23.5 mgP < 0.05
Bone Ca resorption (VO-)Not different−636 ± 243 mg−692 ± 252 mgP > 0.05
Urinary Ca — Urinary Ca over full 24-h collection did not differ
P > .05

Circulating ionized Ca (iCa) and parathyroid hormone (PTH) · during each session

iCa decreased and PTH increased during each EX session; unchanged during REST
P < 0.001

Original publication

Load carriage exercise increases calcium absorption and retention in healthy young women. J Bone Miner Res. Published 4 January 2024. doi:10.1093/jbmr/zjad003

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