The association of obesity with post-cesarean inpatient opioid consumption
Authors' conclusion
Maternal obesity was not associated with higher hourly MME consumption during inpatient stay after cesarean birth. However, patients with obesity and morbid obesity were significantly more likely to be in the top quartile of MME hourly consumption.
Study context
- Population
- Patients who underwent cesarean birth in 2015–2018
- Participants
- 1,620 patients
- Exposure
- Obese and morbidly obese vs non-obese BMI groups
- Non-obesen = 496reference
- Obesen = 753
- Morbidly obesen = 371
- Outcome
- Post-cesarean opioid consumption starting 24 h after delivery, measured as morphine milliequivalents per hour (MME/h)
Main finding
As reported in the abstract
Opioid consumption (MME/h)
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
| Outcome | aOR (95% CI) | P value | |
|---|---|---|---|
| MME/h consumption in highest quartileObesevs Non-obese | 1.42 (1.07–1.89) | P = 0.016 | |
| MME/h consumption in highest quartileMorbidly obesevs Non-obese | 1.60 (1.16–2.22) | P = 0.005 | |
| 0.512Adjusted odds ratio (log scale) |
MME/h consumption in highest quartile
- Obese and morbidly obese more likely to be in highest quartile than non-obese (p < 0.001)
Original publication
The association of obesity with post-cesarean inpatient opioid consumption. Int J Obes (Lond). Published 6 December 2023. doi:10. 1038/ s41366-023-01424-z
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