Obesity

The association of obesity with post-cesarean inpatient opioid consumption

Int J Obes (Lond)Published Retrospective cohort study

Authors' conclusion

Maternal obesity was not associated with higher hourly MME consumption during inpatient stay after cesarean birth. However, patients with obesity and morbid obesity were significantly more likely to be in the top quartile of MME hourly consumption.

Study context

Population
Patients who underwent cesarean birth in 2015–2018
Participants
1,620 patients
Exposure
Obese and morbidly obese vs non-obese BMI groups
  • Non-obesen = 496reference
  • Obesen = 753
  • Morbidly obesen = 371
Outcome
Post-cesarean opioid consumption starting 24 h after delivery, measured as morphine milliequivalents per hour (MME/h)

Main finding

As reported in the abstract

Opioid consumption (MME/h)

P < 0.001

Observational data: associations, not effects.

Secondary outcomes

OutcomeaOR (95% CI)P value
MME/h consumption in highest quartileObesevs Non-obese1.42 (1.07–1.89)P = 0.016
MME/h consumption in highest quartileMorbidly obesevs Non-obese1.60 (1.16–2.22)P = 0.005

MME/h consumption in highest quartile

Obese and morbidly obese more likely to be in highest quartile than non-obese (p < 0.001)

Original publication

The association of obesity with post-cesarean inpatient opioid consumption. Int J Obes (Lond). Published 6 December 2023. doi:10.1038/s41366-023-01424-z

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