The association of diabetes with progression of sleep‐disordered breathing based on a prospective cohort
Main finding · AHI changeResult — go to the resultIncrease 2.52 events per hour 95% CI 0.45–4.59Authors' conclusion
Baseline diabetes was associated with worsening sleep-disordered breathing over 5 years, which mainly increased the change in AHI and oAI.
Study context
- Population
- Sleep Heart Health Study participants who underwent two polysomnograms at a 5-year interval
- Participants
- 2,603 participants
- Exposure
- Baseline diabetes vs no diabetes
- Diabetesn = 161
- Outcome
- Change in apnoea-hypopnoea index (AHI)
- Follow-up
- 5 years
Methodological detailsgeneral linear models adjusted for demographics, lifestyles, history of hypertension, pulmonary function, length of follow-up and baseline apnoea-hypopnoea index (AHI)
- General linear models adjusted for demographics, lifestyles, history of hypertension, pulmonary function, length of follow-up and baseline AHI
Main finding
AHI change
Increase
2.52 events per hour
95% CI 0.45–4.59
P = 0.017
Diabetesvs Without diabetes
increase 2.52 events per hour (95% CI 0.45–4.59); P = 0.017
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Increase (events per hour) (95% CI) | P value | |
|---|---|---|---|
| Obstructive apnoea index (oAI) change · 5 years | 1.13 (0.04–2.23) | P = 0.042 | |
| −10123Difference, events per hour (linear scale) |
Baseline and follow-up AHI and obstructive apnoea index (oAI)
- Diabetes had higher baseline and larger increases in follow-up AHI and oAI vs without diabetes
Subgroups by baseline OSA severity and BMI
- Association consistent across baseline obstructive sleep apnoea severity and BMI groups
Original publication
The association of diabetes with progression of sleep‐disordered breathing based on a prospective cohort. Diabetes Obes Metab. Published 1 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →