The association of atherogenic index of plasma with cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis
Pooled result · MACEResult — go to the resultRelative risk 1.63 95% CI 1.44–1.85Authors' conclusion
The results of this study demonstrated that increased AIP is an independent prognostic factors in patients with CAD. Further research is warranted to elucidate the potential development of targeted interventions to modify AIP levels and improve patient outcomes.
Study context
- Population
- Patients with coronary artery disease (CAD); PubMed, Scopus, Web of Science searched from inception through 2024
- Participants
- 20,833 patients16 studies
- Comparison
- Highest vs lowest atherogenic index of plasma (AIP)
- Outcome
- MACE
Pooled result
As reported in the abstract
Relative risk
1.63
95% CI 1.44–1.85
P < 0.001
Highest AIPvs Lowest AIP
RR 1.63 (95% CI 1.44–1.85); P < 0.001
Further pooled results
Major cardiovascular events (MACE), AIP as continuous variable
- RR
- 1.54 (95% CI, 1.30-1.83; P < 0.001)
Cardiovascular death, elevated AIP
- RR
- 1.79 (95% CI, 1.09-2.78; P = 0.02)
Myocardial infarction (MI), elevated AIP
- RR
- 2.21 (95% CI, 1.55-3.13; P < 0.001)
Revascularization, elevated AIP
- RR
- 1.62 (95% CI, 1.34-1.97; P < 0.001)
No-reflow phenomenon, elevated AIP
- RR
- 3.12 (95% CI, 1.09-8.96; P = 0.034)
Stent thrombosis, elevated AIP
- RR
- 13.46 (95% CI, 1.39-129.02; P = 0.025)
All-cause death and stroke
- AIP not significantly associated with all-cause death and stroke
Original publication
The association of atherogenic index of plasma with cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis. Cardiovasc Diabetol. Published 2 April 2024. doi:10.
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