Tall stature and gigantism in adult patients with acromegaly
Authors' conclusion
In a group of 135 consecutive adult patients with acromegaly, 23% had increased height based on country-specific and MPH data: 13% presented with gigantism while 10% had TS. The frequency of gigantism and TS in patients diagnosed with GH excess as adults is not higher in males than in females. Patients with acromegaly come from normal-stature families.
Study context
- Population
- Adults diagnosed with acromegaly, no family history of growth hormone (GH) excess
- Participants
- 135 consecutive patients
- Outcome
- Height of adult patients with GH excess relative to mid-parental height (MPH) and population mean; categories: normal stature, TS, gigantism
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
Height categories
Gigantism (53% females)
13%
17/135
Tall stature (TS) (57% females)
10%
14/135
Increased height (gigantism or TS)
23%
Observational data: associations, not effects.
Further findings
Height of parents and adult siblings
- Parents and adult siblings were not taller than the population mean
Original publication
Tall stature and gigantism in adult patients with acromegaly. Eur J Endocrinol. Published 23 February 2024. doi:10.
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