Supported Open-Source Automated Insulin Delivery for Management of Type 1 Diabetes in Pregnancy
Authors' conclusion
SOSAID systems represent a promising tool for managing T1D in pregnancy and were successful in reaching target pregnancy glycemia in this single-center cohort.
Study context
- Population
- Pregnant women with T1D whose pregnancy was managed on supported open-source AID (SOSAID) at BCDiabetes, January 2023–October 2024; mean age 33 years, mean pre-pregnancy A1c 6.7% (range 5.8%-8.0%)
- Participants
- 10 women
- Outcome
- TIR (63-140 mg/dL)
- Follow-up
- Trimester 2 and trimester 3
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Mean TIR, trimester 2
68%
Mean TIR, trimester 3
70%
Observational data: associations, not effects.
Further findings
Median 14-day TIR in patients commencing SOSAID during pregnancy (n=7) · pre-SOSAID to immediately after commencing SOSAID
- Median 14-day TIR pre-SOSAID
- 52%
- Median 14-day TIR immediately after commencing SOSAID
- 71%
Obstetric and neonatal outcomes
- Perinatal deaths
- 0
- Congenital anomalies
- 0
- Pre-term delivery
- 1/10
- Hypertensive disorders of pregnancy
- 2/10
- Birthweight above 4 kg
- 3/10
- Neonatal hypoglycemia
- 4/10
Safety
- Episodes of DKA
- 0
- Episodes of severe hypoglycemia
- 0
Original publication
Supported Open-Source Automated Insulin Delivery for Management of Type 1 Diabetes in Pregnancy. J Diabetes Sci Technol. Published 17 May 2025. doi:10.
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