Subacute thyroiditis during pregnancy: clinical characteristics of seven cases
Authors' conclusion
Patients who develop SAT during pregnancy may have less fever than non-pregnant patients with SAT. There were no pregnancy complications in the pregnancy group in this study. This suggests that adverse pregnancy outcomes may be avoided by the appropriate management of SAT, including hypothyroidism after destructive thyroiditis.
Study context
- Population
- Pregnant patients diagnosed with subacute thyroiditis (SAT) at one institution, January 2004 to December 20217 pregnant cases
- Participants
- 7 vs 217
- Exposure
- SAT during pregnancy vs non-pregnant women with SAT
- Pregnancyn = 7
- Non-pregnancyn = 217reference
- Outcome
- Clinical characteristics of SAT in pregnancy at diagnosis
- Follow-up
- At SAT diagnosis
Methodological detailssingle-centre, comparison with non-pregnant SAT patients
- Single-centre
- Comparison with non-pregnant SAT patients
Main finding
As reported in the abstract
- Age, median (range)
- 34 (31-42) years
- Duration of pregnancy, median (range)
- 5 (4-24) weeks
- Neck pain
- all patients
- Fever
- no patients
- FT4, median (range)
- 2.66 (1.14-7.77) ng/dL
- FT3, median (range)
- 7.1 (3.3-16.1) pg/mL
- C-reactive protein, median (range)
- 2.22 (0.42-5.79) mg/dL
- Hypoechoic thyroid lesion
- all patients
- Treated with steroids
- 3 (43%)
- LT4 replacement for hypothyroidism after destructive thyroiditis
- 3 (43%)
Observational data: associations, not effects.
Further findings
Body temperature above 37°C · lower in pregnancy group
Safety
- Pregnancy complications
- 0 · events
Original publication
Subacute thyroiditis during pregnancy: clinical characteristics of seven cases. Eur Thyroid J. Published 14 October 2024. doi:10.
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