Subacute Thyroiditis Following COVID-19 and COVID-19 Vaccination
Authors' conclusion
Based on this large population study, no association was found between COVID-19 infection and/or the COVID-19 vaccine and SAT.
Study context
- Population
- Adults insured by Clalit Health Services (population of 3 million), March 2020 to September 2022matched 1:10
- Participants
- 3,221 vs 32,210
- Comparison
- Subacute thyroiditis (SAT) cases vs matched controls: prior COVID-19 vaccination or infection
- SATn = 3,221
- Controlsn = 32,210reference
- Outcome
- Association of COVID-19 infection and/or COVID-19 vaccination (first, second or third dose) before SAT diagnosis/index date with SAT
- Follow-up
- 30, 60 and 90 days
Methodological detailspopulation-based, 1:10 matched, multivariate conditional logistic regression
- Population-based
- 1:10 matched
- Multivariate conditional logistic regression
Main finding
As reported in the abstract
- No difference between groups in COVID-19 vaccination or infection at 30, 60 and 90 days
- SAT vs Controls: P = 0.880
- SAT vs Controls: P = 0.335
- SAT vs Controls: P = 0.174
- SAT vs Controls: P = 0.735
- SAT vs Controls: P = 0.362
- SAT vs Controls: P = 0.956
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Use of medications for thyroiditis treatmentBetween SAT and Controls · nonsteroidal anti-inflammatory drugs | P < 0.01 |
| Use of medications for thyroiditis treatmentBetween SAT and Controls · steroids | P < 0.01 |
| Use of medications for thyroiditis treatmentBetween SAT and Controls · beta-blockers | P < 0.01 |
Use of medications for thyroiditis treatment
- Higher use of medications for thyroiditis, incl. NSAIDs, steroids and beta-blockers
Original publication
Subacute Thyroiditis Following COVID-19 and COVID-19 Vaccination. Endocr Pract. Published 8 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →