Static and Dynamic Balance Is Impaired in Patients With Long‐Term, Well‐Controlled Acromegaly: A Cross‐Sectional Study
Authors' conclusion
Both static and dynamic balance is impaired in patients with long-term controlled acromegaly, warranting clinical attention. Further studies are needed to address therapeutic options for this overlooked and potentially serious complication.
Study context
- Population
- Patients with long-term, well-controlled acromegaly and age- and sex-matched controls
- Participants
- 17 vs 17
- Exposure
- Long-term acromegaly vs non-acromegalic controls
- Acromegalyn = 17
- Controlsn = 17reference
- Outcome
- Balance: force platform CoP area and velocity, TUG test
Methodological detailsage- and sex-matched controls
- Age- and sex-matched controls
Main finding
As reported in the abstract
Static and dynamic balance
β
2.24
CI 1.29–3.92P = 0.01
CoParea during difficult executive task, with cushion
β
2.09
CI 1.02–4.26P = 0.04
CoParea during difficult executive task, without cushion
β
1.24
CI 0.07–2.42P = 0.04
Mean timed up-and-go (TUG) time; higher with acromegaly
Observational data: associations, not effects.
Further findings
Correlation of TUG time with self-reported joint pain
- β
- 0.04 [0.0004; 0.08], p = 0.05
Original publication
Static and Dynamic Balance Is Impaired in Patients With Long‐Term, Well‐Controlled Acromegaly: A Cross‐Sectional Study. Clin Endocrinol (Oxf). Published 5 August 2025. doi:10.
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