Morphometric study of the pituitary gland and stalk with emphasis on lifestyle factors
Authors' conclusion
This study provides updated morphometric data for the pituitary gland and stalk, incorporating lifestyle-related variables. Smoking and sex were associated with pituitary area, while BMI correlated with stalk length.
Study context
- Population
- Individuals undergoing brain magnetic resonance imaging (MRI), with lifestyle data from questionnaires
- Participants
- 167 individuals
- Outcome
- Pituitary gland and stalk morphometrics (pituitary area, stalk thickness, stalk angle, stalk length) and their associations with demographic and lifestyle factors
Methodological detailsmid-sagittal T1-weighted MRI, multivariable linear regression
- Mid-sagittal T1-weighted MRI
- Multivariable linear regression
Main finding
As reported in the abstract
- Pituitary area, median
- 37.3 mm²
- Male sex associated with smaller pituitary area (multivariable)
- p < 0.01
- Smoking history associated with smaller pituitary area (multivariable)
- p = 0.03
- Male sex associated with larger stalk angle
- p = 0.02
- Higher BMI correlated with longer stalk length
- p = 0.02
Observational data: associations, not effects.
Original publication
Morphometric study of the pituitary gland and stalk with emphasis on lifestyle factors. Pituitary. Published 31 July 2025. doi:10.
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