Sleep Optimization to Improve Glycemic Targets in Adults With Type 1 Diabetes: A Randomized Controlled Parallel Intervention Trial
Authors' conclusion
Sleep-Opt did not improve glycemic targets or sleep parameters, although sleep improved in both intervention groups. Glycemic benefits were observed in participants with suboptimal A1C, suggesting a possible role of sleep intervention in this patient group.
Study context
- Population
- Adults with T1D and short (<6.5 h/night) or irregular (variability of sleep duration ≥1 h) sleep
- Participants
- 73 vs 71
- Comparison
- Sleep-Opt vs Healthy Living
- Sleep-Optn = 73
- Healthy Livingn = 71reference
- Primary endpoint
- A1C, CGM and objective sleep
- Follow-up
- 12 weeks
Methodological detailsparallel, attention control, remotely delivered
- Parallel
- Attention control
- Remotely delivered
Primary result
As reported in the abstract
A1C and CGM parameters
- No significant differences between groups in A1C and CGM parameters
- Sleep duration increased at 6 weeks in both groups; no significant differences between groups at any time point
Further findings
| Outcome | Median difference (95% CI) | |
|---|---|---|
| Diabetes distress · 6 weeks | −0.18 (−0.35 to −0.01) | |
| −0.4−0.200.2Difference (linear scale) |
| Outcome | Estimate | P value |
|---|---|---|
| Subjective sleep quality · 6 weeks | −0.96 (CI −0.17 to −0.23) | |
| A1C in subgroup with baseline A1C ≥7% · 12 weeks | marginal mean −3.5 mmol/mol (95% CI −7.0 to −0.1) | P = 0.047 |
- Diabetes distress: reduced with Sleep-Opt at 6 weeks but not at other time points
- Subjective sleep quality: improved with Sleep-Opt at 6 weeks but not at other time points
A1C in subgroup with baseline A1C ≥7% · 12 weeks
- Significant interaction: intervention effect depended on baseline A1C level
Sleep duration
- Sleep duration increased at 6 weeks in both groups; no significant differences between groups at any time point
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Sleep Optimization to Improve Glycemic Targets in Adults With Type 1 Diabetes: A Randomized Controlled Parallel Intervention Trial. Diabetes Care. Published 18 May 2026. doi:10.
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