Health Inequities in Older Adults With Type 1 Diabetes: A Nationwide Registry Analysis of Sociodemographic and Clinical Profiles for Glycaemic Control and Complications
Authors' conclusion
Older adults with Type 1 diabetes exhibit a unique clinical profile of poor glycaemic control and a high burden of complications, influenced by regional GDP disparities.
Study context
- Population
- Patients with T1D in the China Diabetes Type 1 Study (CD1S), 69 centres across China, 2016–2021
- Participants
- 9,637 patients
- Exposure
- Older adults vs young adults vs <18 years with T1D
- Outcome
- Achievement of target HbA1c
Methodological detailsreal-world data, 69 centres, random forest model with SHAP values
- Real-world data
- 69 centres
- Random forest model with SHAP values
Main finding
As reported in the abstract
P < 0.05
- Older adults with at least one chronic complication
- 81.0%
Observational data: associations, not effects.
Further findings
Predictors of HbA1c
- Longer duration, higher BMI and higher gross domestic product (GDP) significantly associated with lower HbA1c
- all p < 0.05
Complications in higher-GDP regions vs middle- and low-GDP regions
- Diabetic retinopathy (reduced with higher GDP)
- 19.7%
- Nephropathy (reduced with higher GDP)
- 13.6%
- Peripheral neuropathy (reduced with higher GDP)
- 46.9%
- Peripheral vasculopathy (higher with higher GDP)
- 41.8%
Original publication
Health Inequities in Older Adults With Type 1 Diabetes: A Nationwide Registry Analysis of Sociodemographic and Clinical Profiles for Glycaemic Control and Complications. Diabetes Obes Metab. Published 18 May 2026. doi:10. 1111/ dom. 70833
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