Sociodemographic inequities and use of hybrid closed-loop systems associated with obesity in youth with type 1 diabetes
Authors' conclusion
This study revealed increasing rates of obesity in children with type 1 diabetes and identified sociodemographic and diabetes care-related factors associated with obesity, highlighting targets for intervention to decrease future risk of cardiovascular complications.
Study context
- Population
- Youth with T1D for ≥1 year followed at a pediatric tertiary care academic medical center, 2018–2023
- Participants
- 2,242 participants7,360 visits
- Outcome
- Changes over time in rates of overweight and obesity; factors associated with obesity
Methodological detailssingle-centre, pediatric tertiary care academic medical center, multivariable generalized estimating equations (GEE) analysis, conditional logistic regression
- Single-centre
- Pediatric tertiary care academic medical center
- Multivariable GEE analysis
- Conditional logistic regression
Main finding
As reported in the abstract
Adjusted annual percentage of patients with obesity · 2018 to 2023
- Obesity in 2018
- 13.8 %
- Obesity in 2023
- 18.2 %
- Increase over time
- P = 0.006
Observational data: associations, not effects.
Further findings
Factors associated with obesity (multivariable GEE)
- Public insurance
- P = 0.026
- Lower Child Opportunity Index score
- P = 0.027
- Use of hybridclosed-loop (HCL) systems
- P = 0.023
Factors associated with obesity (conditional logistic regression (CLR))
- Use of CGM and HCL systems and the sum of their effects associated with obesity
- P = 0.002
- Each patient had both control (not obesity) and case (obesity) status
Original publication
Sociodemographic inequities and use of hybrid closed-loop systems associated with obesity in youth with type 1 diabetes. Diabetes Res Clin Pract. Published 9 February 2025. doi:10.
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