Sex-specific differences in the effect of the atherogenic index of plasma on prediabetes and diabetes in the NHANES 2011–2018 population
Authors' conclusion
This study showed that a higher AIP was significantly associated with an increased prevalence of prediabetes and diabetes, and the above relationships occurred only among women and not men.
Study context
- Population
- American adults; mean age 48.51 ± 18.42 years; mean atherogenic index of plasma (AIP) - 0.09 (SD 0.34)
- Participants
- 10,099 adults
- Exposure
- AIP per 1-unit increment, by sex
- Outcome
- Prediabetes and diabetes
Main finding
As reported in the abstract
| Group | OR |
|---|---|
| Female | 4.96 (95% CI 2.68, 9.18) |
| Male | 1.41 (95% CI 0.87, 2.29) |
OR
Female4.96 (95% CI 2.68, 9.18)
Male1.41 (95% CI 0.87, 2.29)
- Female vs Male: P for interaction < 0.0001
Observational data: associations, not effects.
Further findings
Prediabetes and diabetes per 1-unit increment in AIP, overall
- OR
- 2.49 (95% CI 1.75, 3.54)
Prevalence
- Prediabetes
- 40.24%
- Diabetes
- 21.32%
Baseline characteristics
- Age, years (mean ± SD)
- 48.51 ± 18.42
- AIP, mean (SD)
- - 0.09 (0.34)
Original publication
Sex-specific differences in the effect of the atherogenic index of plasma on prediabetes and diabetes in the NHANES 2011–2018 population. Cardiovasc Diabetol. Published 30 January 2023. doi:10. 1186/ s12933-023-01740-8
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