Type 2 & other diabetes

Sex-specific differences in the effect of the atherogenic index of plasma on prediabetes and diabetes in the NHANES 2011–2018 population

Cardiovasc DiabetolPublished Cross-sectional study

Authors' conclusion

This study showed that a higher AIP was significantly associated with an increased prevalence of prediabetes and diabetes, and the above relationships occurred only among women and not men.

Study context

Population
American adults; mean age 48.51 ± 18.42 years; mean atherogenic index of plasma (AIP) - 0.09 (SD 0.34)
Participants
10,099 adults
Exposure
AIP per 1-unit increment, by sex
Outcome
Prediabetes and diabetes

Main finding

As reported in the abstract

GroupOR
Female4.96 (95% CI 2.68, 9.18)
Male1.41 (95% CI 0.87, 2.29)

OR

Female4.96 (95% CI 2.68, 9.18)
Male1.41 (95% CI 0.87, 2.29)
  • Female vs Male: P for interaction < 0.0001

Observational data: associations, not effects.

Further findings

Prediabetes and diabetes per 1-unit increment in AIP, overall

OR
2.49 (95% CI 1.75, 3.54)

Prevalence

Prediabetes
40.24%
Diabetes
21.32%

Baseline characteristics

Age, years (mean ± SD)
48.51 ± 18.42
AIP, mean (SD)
- 0.09 (0.34)

Original publication

Sex-specific differences in the effect of the atherogenic index of plasma on prediabetes and diabetes in the NHANES 2011–2018 population. Cardiovasc Diabetol. Published 30 January 2023. doi:10.1186/s12933-023-01740-8

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