Sex differences in response to lifestyle intervention among children and adolescents: Systematic review and meta‐analysis
Authors' conclusion
The meta-analysis revealed that youth with overweight or obesity do not demonstrate a differential response to lifestyle intervention in relation to adiposity-related outcomes.
Study context
- Population
- Children and adolescents aged 6 to 18 years with overweight or obesity randomised to lifestyle intervention vs control49 studies
- Comparison
- Sex differences in response to lifestyle intervention vs control
- Outcome
- Sex differences in adiposity following lifestyle intervention
Methodological detailsmeta-regression, Searched PubMed, Web of Science, MEDLINE to March 2021; 89 full-text articles reviewed, Authors contacted for sex-specific summary statistics (n = 14/49)
- Meta-regression
- Searched PubMed, Web of Science, MEDLINE to March 2021; 89 full-text articles reviewed
- Authors contacted for sex-specific summary statistics (n = 14/49)
Pooled result
As reported in the abstract
Sex difference in treatment effect on adiposity (meta-regression)
- SE = 0.18, z = −0.28
- beta (weight) −0.05; P = 0.8
- SE = 0.14, z = 0.19
- beta (BMI) 0.03; P = 0.85
- SE = 0.18, z = −0.23
- beta (BMI z score) −0.04; P = 0.82
- SE = 0.16, z = −0.67
- beta (percentage body fat) −0.11; P = 0.51
- SE = 0.25, z = −1.18
- beta (waist circumference) −0.30; P = 0.24
Further pooled results
Studies reporting significant intervention effects on adiposity
- Studies with statistically significant intervention effects on adiposity
- 33 (67%)
- Studies evaluating sex differences (conflicting results)
- 2 (4%)
Original publication
Sex differences in response to lifestyle intervention among children and adolescents: Systematic review and meta‐analysis. Obesity (Silver Spring). Published 10 February 2023. doi:10.
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