Serum triglyceride glucose index is a valuable predictor for visceral obesity in patients with type 2 diabetes: a cross-sectional study
Authors' conclusion
. TyG is a comprehensive indicator of adipose volume, density, and distribution in patients with T2DM and is a valuable predictor for VO in combination with anthropometric indices, such as BMI.
Study context
- Population
- Patients with T2D; abdominal adipose characteristics from CT at lumbar 2/3 level
- Participants
- 976 patients
- Exposure
- Triglyceride glucose (TyG) index vs body mass index (BMI) and TyG-BMI for predicting visceral obesity
- Outcome
- Predictive value of the TyG index for visceral obesity (VO)
Main finding
As reported in the abstract
TyG index by VO status
- TyG, males: Visceral obesity (VO) vs non-VO
- 9.74 vs. 8.88
- TyG, females: VO vs non-VO
- 9.59 vs. 9.01
- TyG independent factor for VO, males (OR)
- 2.997
- TyG independent factor for VO, females (OR)
- 2.233
- TyG AUC for VO, males (second to BMI)
- 0.770
- TyG AUC for VO, females (second to BMI)
- 0.720
Observational data: associations, not effects.
Further findings
Correlations of TyG with adipose characteristics
- TyG positively correlated with visceral adipose area (VAA), subcutaneous adipose area (SAA) and VAA-to-SAA ratio (VSR); negatively with visceral adipose density (VAD) and subcutaneous adipose density (SAD)
TyG-BMI vs BMI for predicting VO
- Males: TyG-BMI AUC vs BMI AUC (significantly higher with TyG-BMI)
- 0.879 vs 0.835
- Females: TyG-BMI AUC vs BMI AUC (no significant difference)
- 0.865 vs 0.835
Combined higher BMI and TyG
- Patients with higher BMI and TyG had significantly higher VO risk than other patients
Original publication
Serum triglyceride glucose index is a valuable predictor for visceral obesity in patients with type 2 diabetes: a cross-sectional study. Cardiovasc Diabetol. Published 29 April 2023. doi:10.
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