Serum Calcium Normal Range in 1,000 Term Newborns
Authors' conclusion
We established that the expected serum calcium in neonates ranges between 2.06 mmol/L and 2.73 mmol/L which is significantly wider than the adult range. This finding should help physicians in the diagnosis of hypo- or hypercalcemia. In addition, our study supports the importance of vitamin D supplementation and 25(OH)D status for neonatal serum calcium maintenance.
Study context
- Population
- Term newborns and their mothers, two centres near Paris, France, April 2012–July 2014
- Participants
- 1,002 mother-newborn dyads
- Exposure
- Vitamin D-supplemented vs non-supplemented mothers
- Outcome
- Normal range of neonatal total serum calcium
- Follow-up
- 3 days of life
Methodological detailstwo centres
- Two centres
Main finding
As reported in the abstract
Total serum calcium
Range [2.5 and 97.5 percentiles]
2.06 mmol/L to 2.73 mmol/L
Mean
2.45 mmol/L
Observational data: associations, not effects.
Further findings
Serum calcium by maternal vitamin D supplementation
- Serum calcium similar between babies of vitamin D-supplemented and non-supplemented mothers
Determinants of newborn serum calcium
- Maternal and cord blood 25(OH)D concentrations important for newborn serum calcium maintenance in univariate and multivariable analyses
Original publication
Serum Calcium Normal Range in 1,000 Term Newborns. Horm Res Paediatr. Published 12 March 2024. doi:10.
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