Screening for Gastric Sensory Motor Abnormalities in Pediatric Patients With Type 1 Diabetes
Authors' conclusion
Gastrointestinal symptoms related to gastric sensory motor abnormalities are seen in youth and young adults with type 1 diabetes. In particular, for those with higher GCSI scores, earlier recognition and referral may be warranted.
Study context
- Population
- Youth with T1D aged 12 to 25 years; Gastroparesis Cardinal Symptom Index (GCSI) questionnairecompleted GCSI
- Participants
- 359 participants
- Outcome
- Frequency of gastric sensory motor symptoms (GCSI questionnaire)
Methodological detailsprospective, plus 5-year retrospective review of gastric emptying scans
- Prospective
- Plus 5-year retrospective review of gastric emptying scans
Main finding
As reported in the abstract
Gastrointestinal symptoms among responders
≥1 gastrointestinal symptom
270
75%
Nausea (most common symptom)
71%
GCSI score ≥1.9 (more severe symptoms)
17%
Observational data: associations, not effects.
Further findings
Age, GCSI score ≥1.9 vs <1.9
- Participants with scores ≥1.9 were older: 19.1 ± 3.0 vs 17.8 ± 3.3 years
- P = 0.01
Responders vs nonresponders
- Non-Hispanic White, 90% vs 86%
- P = 0.003
- Female, 58% vs 44%
- P < 0.0001
- Lower HbA1c, 8.1 ± 1.8 vs 9.0 ± 2.1
- P < 0.0001
Delayed gastric emptying on scan (retrospective study) · January 2015 to December 2019
- Underwent gastric emptying scan
- 778
- Had T1D
- 29
- T1D with delayed gastric emptying
- 11 (38%)
Original publication
Screening for Gastric Sensory Motor Abnormalities in Pediatric Patients With Type 1 Diabetes. Endocr Pract. Published 23 December 2022. doi:10.
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