Safety and Effectiveness of the Use of an Electronic Glucose Monitoring System Versus Weight-Based Dosing Nomogram for Treatment of Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome in a VA Hospital
Authors' conclusion
While the primary endpoint of decreased hypoglycemia was not found to be statistically significant, it did reduce the overall number of hypoglycemia events in the eGMS group compared with the PBP group which may be clinically significant. This demonstrates that eGMS use has the potential to minimize hypoglycemia and glycemic variability in a critically-ill Veteran population by individualizing insulin drip titration based on a variety of patient-specific factors and providing reminders for staff to obtain BG checks in a timely manner.
Study context
- Population
- Patients with diabetic ketoacidosis (DKA) or hyperglycemic hyperosmolar syndrome (HHS) on an insulin drip, treated in the emergency department (ED) or intensive care unit (ICU) at Veteran Health Indiana
- Participants
- 168 patients
- Exposure
- Electronic glucose monitoring system (eGMS) vs paper-based protocol
- eGMSn = 84
- PBPn = 84reference
- Outcome
- Percentage of patients with hypoglycemia (BG <70 mg/dL)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Hypoglycemia (BG <70 mg/dL)
P = 0.90
Observational data: associations, not effects.
Secondary outcomes
| Outcome | P value |
|---|---|
| Glucose checks drawn within protocol recommendation80.7% vs 52.6%; statistically significant | P = 0.02 |
Original publication
Safety and Effectiveness of the Use of an Electronic Glucose Monitoring System Versus Weight-Based Dosing Nomogram for Treatment of Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome in a VA Hospital. J Diabetes Sci Technol. Published 7 February 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →