Type 2 & other diabetes

Role-Playing–Based Physician Training and Metabolic Outcomes Among Patients With Type 2 Diabetes: A Cluster Randomized Clinical Trial

JAMA Netw OpenPublished Cluster randomised controlled trial

Primary result · HbA1c <7.0%Result — go to the resultAdjusted between-group difference 16.6% 95% CI 7.2%–25.7%

Authors' conclusion

In this cluster randomized clinical trial of role-playing-based intensive training for physicians managing type 2 diabetes, the intervention significantly improved patient glycemic control.

Study context

Population
Patients with T2D treated by physicians from qualified diabetes centers across China; patients mean age 53.0 years, 35.3% women; 205 physicians randomised (103 vs 102)205 physicians
Participants
2,017 patients
Comparison
Role-playing-based intensive physician training vs regular training
  • Intensive trainingn = 1,009
  • Regular trainingn = 1,008reference
Primary endpoint
Proportion of patients achieving hemoglobin A1c (HbA1c) <7.0%
Follow-up
6 months
Methodological detailsopen-label, 2-arm parallel, cluster randomized, 205 centers in China, Enrollment February 13 to September 19, 2023; 12-month follow-up completed October 25, 2024
  • Open-label
  • 2-arm parallel
  • Cluster randomized
  • 205 centers in China
  • Enrollment February 13 to September 19, 2023; 12-month follow-up completed October 25, 2024

Primary result

HbA1c <7.0%

Adjusted between-group difference

16.6%

95% CI 7.2%–25.7%

P < 0.001

Events by treatment group

Intensive trainingvs Regular training
adjusted between-group difference 16.6% (95% CI 7.2%–25.7%); P < 0.001

As reported in the abstract

Further findings

OutcomeIntensive trainingRegular trainingAdjusted between-group difference (95% CI)P value
HbA1c <7.0% · 12 months60.9%44.6%17.0% (7.0%–26.8%)P < 0.001
Reduction in BMI−0.3 (−0.5 to −0.1)
OutcomeAdjusted between-group difference (cm) (95% CI)
Reduction in waist circumference−1.4 (−2.1 to −0.8)
OutcomeAdjusted between-group difference (mg/dL) (95% CI)
Reduction in fasting glucose−6.3 (−10.7 to −1.9)
OutcomeAdjusted between-group difference (mm Hg) (95% CI)
Reduction in systolic blood pressure−1.5 (−2.9 to −0.1)

Safety

Serious adverse events

Serious adverse events

Serious adverse events were comparable between groups

Original publication

Role-Playing–Based Physician Training and Metabolic Outcomes Among Patients With Type 2 Diabetes: A Cluster Randomized Clinical Trial. JAMA Netw Open. Published 3 August 2026. doi:10.1001/jamanetworkopen.2026.27376

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