Role of subclinical hypothyroidism on kidney damage in children with obesity
Main finding · Kidney damageResult — go to the resultAdjusted odds ratio 2.04 95% CI 1.15–3.61Authors' conclusion
Although preliminary, our data suggested an increased risk of KD in children with obesity and SH.
Study context
- Population
- Children with obesity
- Participants
- 355 children
- Exposure
- SCH vs no SCH in children with obesity
- Outcome
- Kidney damage: eGFR<90 mL/min/1.73 m² and/or hypertension and/or albuminuria (≥30 mg/g urinary creatinine)
Main finding
Kidney damage
Adjusted odds ratio
2.04
95% CI 1.15–3.61
P = 0.015
SHvs Without SH
aOR 2.04 (95% CI 1.15–3.61); P = 0.015
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| eGFRLower eGFR with SH | P = 0.001 |
eGFR vs thyroid stimulating hormone (TSH) (general linear model)
- Inverse association of eGFR with TSH levels
- P < 0.0001
Original publication
Role of subclinical hypothyroidism on kidney damage in children with obesity. Int J Obes (Lond). Published 23 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →