Impact of weight loss on obesity‐related complications and direct healthcare costs in Japan: A modelling study
Authors' conclusion
Weight loss in the Japanese population has the potential to drive major reductions in healthcare costs via prevention of complications associated with higher BMI and consequent reductions in costs associated with these complications. Greater weight loss is likely to be associated with greater cost reductions. Our analysis highlights the importance of prompt weight management support for people living with obesity.
Study context
- Population
- Simulated cohort of Japanese individuals aged 20–69 years with body mass index (BMI) 25–50 kg/m²; modelled 2024 to 2029simulated cohort
- Participants
- 100,000 participants
- Comparison
- 10% or 15% lower weight vs no weight loss
- Outcome
- Cumulative direct medical cost reductions
- Follow-up
- Over 5 years
Methodological detailssimulation model, value of weight loss model
- Simulation model
- Value of weight loss model
Main finding
As reported in the abstract
Cumulative cost reduction, 10% weight loss
34.6 million USD
5.2 billion JPY
Cumulative cost reduction, 15% weight loss
47.7 million USD
7.1 billion JPY
Further findings
Total direct medical costs of complications · 2024 to 2029
- Costs in 2024
- 171.7 million US dollars (USD) or 25.6 billion Japanese yen (JPY)
- Projected costs by 2029
- 234.9 million USD (35.1 billion JPY)
Incidence of complications
- 10% or 15% lower weight associated with lower incidence of all complications, particularly sleep apnoea, T2D and hypertension
Original publication
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