Risk of progression to type 2 diabetes or regression to normoglycaemia among Ghanaians with prediabetes living in Ghana and the Netherlands: The RODAM prospective study
Main finding · Regression to normoglycaemiaResult — go to the resultIncident risk ratio 3.48 95% CI 2.39–5.05Authors' conclusion
Among Ghanaians with prediabetes, regression to normoglycaemia was more frequent than progression to T2D, and more likely in non-migrants than in migrants.
Study context
- Population
- Ghanaians with prediabetes (WHO criteria) in the RODAM cohort, living in Ghana or Amsterdam; average follow-up 6.7 years
- Participants
- 615 participants
- Exposure
- Non-migrants vs migrants
- Non-migrantsn = 245
- Migrantsn = 370reference
- Outcome
- Progression to T2D or regression to normoglycaemia
- Follow-up
- Average 6.7 years
Methodological detailsmultinational, adjusted for age, sex, follow-up duration, socioeconomic status, baseline BMI and FPG
- Multinational
- Adjusted for age, sex, follow-up duration, socioeconomic status, baseline BMI and FPG
Main finding
Regression to normoglycaemia · average follow-up 6.7 years
Incident risk ratio
3.48
95% CI 2.39–5.05
P < 0.001
By group
Non-migrantsvs Migrants
incident risk ratio 3.48 (95% CI 2.39–5.05); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
Progression to T2D · average follow-up 6.7 years · unadjusted proportions
P = 0.108
| Outcome | Incident risk ratio (CI) | P value | |
|---|---|---|---|
| Progression to T2D · average follow-up 6.7 yearsFully adjusted | 1.20 (0.71–2.05) | 0.498 | |
| 0.512Incident risk ratio (log scale) |
Overall cumulative incidence of T2D and of normoglycaemia
- Cumulative incidence of T2D, overall
- 12.6%
- Cumulative incidence of normoglycaemia, overall
- 28.9%
Original publication
Risk of progression to type 2 diabetes or regression to normoglycaemia among Ghanaians with prediabetes living in Ghana and the Netherlands: The RODAM prospective study. Diabet Med. Published 15 April 2026. doi:10.
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