Type 2 & other diabetes

Evaluation of Diabetes Risk Models Applied to the Prediction of Incident Dysglycaemia in African and European Populations

Diabetes Obes MetabPublished External validation study of diabetes risk prediction models in prospective cohorts

Authors' conclusion

Existing diabetes risk prediction models can be applied to predict incident dysglycaemia in both Sub-Saharan African and European populations, but only after recalibration to local risk levels.

Study context

Population
Prospective cohorts of African (Ghanaian migrants and non-migrants; urban Black South Africans) and European (Swedish) populations; dysglycaemia by American Diabetes Association criteriathree cohorts
Participants
1,607 / 515 / 3,044
Comparison
African Diabetes Risk, Finnish Diabetes Risk, DESIR and personal and clinical Framingham models
  • RODAM-Prosn = 1,607
  • Middle-aged Soweto cohort (MASC)n = 515
  • Västerbotten Intervention Programme (VIP)n = 3,044
Outcome
Discrimination (c-statistic) and calibration of risk models for incident dysglycaemia, before and after recalibration
Methodological detailsthree prospective cohorts, recalibration
  • Three prospective cohorts
  • Recalibration

Performance

As reported in the abstract

Model performance for incident dysglycaemia

All models demonstrated poor-to-modest discrimination

c-statistic < 0.7

Calibration error after recalibration, RODAM-Pros and VIP

≤ 2.3%

Calibration error after recalibration, MASC

≤ 3.4%

Further findings

Incident dysglycaemia · median follow-up 6.7, 6.7 and 9.9 years, respectively

Original publication

Evaluation of Diabetes Risk Models Applied to the Prediction of Incident Dysglycaemia in African and European Populations. Diabetes Obes Metab. Published 1 September 2026. doi:10.1111/dom.71285

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