Risk of type 2 diabetes mellitus in adult patients with atopic dermatitis
Main finding · New-onset T2DResult — go to the resultAdjusted hazard ratio 1.44 95% CI 1.27–1.63Authors' conclusion
The significant risk of subsequent T2D in adult AD patients suggested the necessity for efforts to prevent T2D in AD patients.
Study context
- Population
- Adults newly diagnosed with atopic dermatitis (AD) and matched controls, National Health Insurance Service-National Sample Cohort 2.0, South Korea, 2002–2015matched cohort
- Participants
- 36,692 vs 36,692
- Exposure
- Adults newly diagnosed with atopic dermatitis vs matched controls
- ADn = 36,692
- Matched controlsn = 36,692reference
- Outcome
- New onset of T2D (ICD-10 code E11)
Methodological detailspropensity score-matching, national database (National Health Insurance Service-National Sample Cohort (NHIS-NSC) 2.0, South Korea, 2002–2015)
- Propensity score-matching
- National database (NHIS-NSC 2.0, South Korea, 2002–2015)
Main finding
New-onset T2D
Adjusted hazard ratio
1.44
95% CI 1.27–1.63
P < 0.001
ADvs Matched controls
aHR 1.44 (95% CI 1.27–1.63); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
T2D risk in subgroups by sex, age and BMI
- Subgroup results by sex, age and BMI consistent with the primary analysis
Sensitivity analyses with different T2D and/or AD definitions
- Sensitivity analyses showed consistent results
Original publication
Risk of type 2 diabetes mellitus in adult patients with atopic dermatitis. Diabetes Res Clin Pract. Published 17 August 2023. doi:10.
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