Clinical Outcomes for Newly Diagnosed Diabetes Patients in Korea: A National Health Insurance Data
Authors' conclusion
Patients newly diagnosed with type 2 diabetes faced substantially increased risks of cardiovascular, renal complications, and all-cause mortality, despite preserved baseline kidney function.
Study context
- Population
- Patients aged 20–80 years newly diagnosed with T2D without prior atherosclerotic CVD or kidney disease (eGFR < 60 mL/min/1.73 m², albuminuria, or relevant ICD codes), Korean National Health Insurance Service databasematched cohort
- Participants
- 2,164,060 patients
- Exposure
- Newly diagnosed T2D vs matched controls
- T2Dn = 432,812
- Outcome
- Ischemic/hemorrhagic stroke, MI, HF, chronic kidney disease (CKD) progression to eGFR < 60 mL/min/1.73 m², renal replacement therapy (RRT) and all-cause mortality
- Follow-up
- Median 5.1 years (IQR 3.3-6.2 years)
Methodological detailsnationwide, age- and sex-matched controls (1:4)
- Nationwide
- Age- and sex-matched controls (1:4)
Main finding
As reported in the abstract
Total composite outcome
T2D vs ControlsEstimate (95% CI)
Adjusted for covariates
HR 1.67(1.64–1.70)
Total composite outcome
HR (non-renal composite outcome) 1.57(1.53–1.60)
Total composite outcome
HR (renal composite outcome) 1.86(1.82–1.90)
Total composite outcome
HR (ischemic stroke) 1.73(1.66–1.80)
Total composite outcome
HR (hemorrhagic stroke) 1.24(1.14–1.35)
Total composite outcome
HR (MI) 1.84(1.73–1.95)
Total composite outcome
HR (HF) 2.17(2.08–2.27)
Total composite outcome
HR (CKD progression) 1.47(1.41–1.53)
Total composite outcome
HR (RRT) 4.17(3.51–4.95)
Total composite outcome
HR (all-cause mortality) 1.14(1.10–1.19)
Observational data: associations, not effects.
Original publication
Clinical Outcomes for Newly Diagnosed Diabetes Patients in Korea: A National Health Insurance Data. Diabetes Obes Metab. Published 16 July 2026. doi:10.
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