Effectiveness of Telehealth Low‐Carbohydrate Intervention in Preventing Chronic Kidney Disease: A Real‐World, Retrospective, Matched Cohort Study
Authors' conclusion
In this large, real-world matched cohort, participation in a telehealth-delivered nutrition therapy emphasising carbohydrate reduction was associated with lower CKD incidence and progression without increased renal adverse events.
Study context
- Population
- Adults (type 2 diabetes and obesity focus) in the Komodo Healthcare Map US claims database, 5 years of follow-upmatched 1:1
- Exposure
- Telehealth low-carbohydrate nutrition therapy vs usual care
- VINTn = 11,077
- Outcome
- New-onset CKD, CKD stage ≥ 3, and CKD stage ≥ 4
- Follow-up
- 5 years
Methodological detailspropensity score-matched, real-world, administrative claims database
- Propensity score-matched
- Real-world
- Administrative claims database
Main finding
As reported in the abstract
New-onset CKD; CKD stage ≥ 3; CKD stage ≥ 4
VINT
10.1 per 1000 person-years
UC
15.6 per 1000 person-years
VINT vs UCHazard ratio (95% CI)P value
New-onset CKD
0.64(0.53–0.77)
P < 0.001CKD stage ≥ 3
0.57(0.45–0.73)
P < 0.001CKD stage ≥ 4
0.38(0.18–0.79)
P = 0.009Observational data: associations, not effects.
Safety
Renal safety events
- No increased risk of kidney stones, metabolic acidosis, DKA, or gout with VINT vs UC
Original publication
Effectiveness of Telehealth Low‐Carbohydrate Intervention in Preventing Chronic Kidney Disease: A Real‐World, Retrospective, Matched Cohort Study. Diabetes Obes Metab. Published 16 July 2026. doi:10.
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