Osteoporosis, bone & mineral

Risk of major osteoporotic fractures among ultra-orthodox Jews

Osteoporos IntPublished Retrospective cohort study

An erratum to this article was published (Osteoporos Int, Sep 2024 ↗)

Main finding · Osteoporotic fractureResult — go to the resultAdjusted hazard ratio 1.026 95% CI 0.95–1.11

Authors' conclusion

We did not find a significant difference in the rate of osteoporotic fractures between Ultra-Orthodox and non-Orthodox populations despite major differences in exposure to potential risk factors.

Study context

Population
Maccabi Health Service patients 65 years and older without a history of osteoporotic fracture, residing in regions of Ultra-Orthodox and non-Orthodox Jews16,352 (14.2%) with fracture
Participants
115,134 patients
Exposure
Residents of Ultra-Orthodox regions vs residents of non-Orthodox regions
  • Ultra-Orthodoxn = 5,397
  • non-Orthodoxn = 109,737reference
Outcome
Adjusted risk of osteoporotic fracture
Follow-up
9 years
Methodological detailsCox regression adjusted for patient characteristics and osteoporosis risk factors
  • Cox regression adjusted for patient characteristics and osteoporosis risk factors

Main finding

Osteoporotic fracture

Adjusted hazard ratio

1.026

95% CI 0.95–1.11

P = 0.512

By group

Ultra-Orthodoxvs non-Orthodox
aHR 1.026 (95% CI 0.95–1.11); P = 0.512

As reported in the abstract

Observational data: associations, not effects.

Further findings

Osteoporotic fracture rate, females (subgroup) · no significant difference

P = 0.982

Osteoporotic fracture rate, males (subgroup) · no significant difference

P = 0.311

Original publication

Risk of major osteoporotic fractures among ultra-orthodox Jews. Osteoporos Int. Published 11 November 2022. doi:10.1007/s00198-022-06522-8

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