Risk Assessment and Coronary Artery Calcium Scoring in Transgender and Gender-Diverse Individuals Receiving Gender-Affirming Hormone Therapy
Authors' conclusion
The presence of CAC in this small cohort of TGD individuals on GAHT was similar to that in the cisgender age-matched population. CAC scoring is a means to assess the prevalence of CAD in TGD individuals and identify those in whom aggressive risk reduction is indicated.
Study context
- Population
- Transgender and gender-diverse (TGD) individuals aged ≥30 years on gender-affirming hormone therapy (GAHT), without known cardiovascular disease (CVD) risk factors other than tobacco use and family history of CVD
- Participants
- 25 vs 22
- Exposure
- Coronary Artery Calcium (CAC) scores in TGD individuals on GAHT vs cisgender age-matched population
- Transwomenn = 25
- Transmenn = 22
- Outcome
- Prevalent coronary artery disease (CAD) by CAC scoring, compared with the general population
Methodological detailscomparison with cisgender age-matched population
- Comparison with cisgender age-matched population
Main finding
As reported in the abstract
CAC score >0 to 99
Observational data: associations, not effects.
Further findings
- Framingham Risk Scores were not correlated with the presence of CAC
Original publication
Risk Assessment and Coronary Artery Calcium Scoring in Transgender and Gender-Diverse Individuals Receiving Gender-Affirming Hormone Therapy. Endocr Pract. Published 17 December 2022. doi:10.
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