Review of the relationship between deficiency of Glucose-6-phosphate dehydrogenase deficiency and diabetes and its complications
Authors' conclusion
Consistent evidence indicates a higher risk of complications associated with G6PD deficiency and diabetes, though associations with diabetes onset remain inconsistent.
Study context
- Population
- Primary studies on G6PD deficiency and diabetes; PubMed, Cochrane Library and Embase searched to August 10th, 202642 studies
- Comparison
- G6PD deficiency vs no G6PD deficiency in diabetes
Methodological detailstwo independent reviewers, Two reviewers independently searched databases, resolving discrepancies by discussion
- Two independent reviewers
- Two reviewers independently searched databases, resolving discrepancies by discussion
Pooled result
As reported in the abstract
- G6PD deficiency was more prevalent in T2D patients than in the general population
- Diagnostic complications identified, including artificially reduced HbA1c
- Specific G6PD variants associated with increased risk and severity of diabetes-associated retinopathy
- G6PD deficiency linked to increased risk of MI, stroke and arterial stiffness
Original publication
Review of the relationship between deficiency of Glucose-6-phosphate dehydrogenase deficiency and diabetes and its complications. Diabetes Res Clin Pract. Published 19 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →