Diabetes technology

Retrospective Comparison of Commercially Available Automated Insulin Delivery With Open-Source Automated Insulin Delivery Systems in Type 1 Diabetes

J Diabetes Sci TechnolPublished Retrospective cohort study

Authors' conclusion

In conclusion, both groups were able to achieve satisfactory glycemic outcomes independent of age, gender, and diabetes duration. However, the PWT1D using OS-AID systems attained an even better glycemic control with no clinical safety concerns.

Study context

Population
People with T1D using MiniMed 670G or OS-AID routinely for 3 to 6 months, February 18, 2020 to January 15, 2023, Austria
Participants
144 people
Exposure
Open-source automated insulin delivery (AID) vs MiniMed 670G
  • OS-AIDn = 28
  • 670Gn = 116reference
Outcome
Quality of glycemic control
Methodological detailsdescriptive analysis, no statistical tests
  • Descriptive analysis
  • No statistical tests

Main finding

As reported in the abstract

Time in range (TIR) 70-180 mg/dL

Observational data: associations, not effects.

Further findings

TAR 181-250 mg/dL

TAR >250 mg/dL

HbA1c

Median glucose

Safety

TBR 54-69 mg/dL

TBR <54 mg/dL

Time below range (TBR) <54 mg/dL

Comparable in both groups

Original publication

Retrospective Comparison of Commercially Available Automated Insulin Delivery With Open-Source Automated Insulin Delivery Systems in Type 1 Diabetes. J Diabetes Sci Technol. Published 16 February 2024. doi:10.1177/19322968241230106

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