Diabetes technology

Comparison of Control‐IQ and open‐source AndroidAPS automated insulin delivery systems in adults with type 1 diabetes: The CODIAC study

Diabetes Obes MetabPublished Prospective single-arm clinical trial

Authors' conclusion

The CODIAC study is the first prospective study investigating the switch between open-source and commercially available AID systems. CIQ and AAPS were comparable in achieving TIR. However, hypoglycaemia was significantly lower with CIQ.

Study context

Population
Adults with T1D who had been using AAPS by their own decision
Participants
25 adults
Exposure
Control-IQ (CIQ) vs AAPS
Outcome
Change in % TIR (70-80 mg/dL as printed)
Follow-up
3 months
Methodological detailsopen-label, sequential switch
  • Open-label
  • Sequential switch

Main finding

As reported in the abstract

TIR

P = 0.12

Observational data: associations, not effects.

Further findings

Mean sensor glucose · no difference

P = 0.21

OutcomeCIQAAPSP value
HbA1cNo difference6.3% ± 2.1%6.4% ± 3.1%P = 0.59

TAR (>180 and >250 mg/dL)

No differences between CIQ and AAPS

Satisfaction with CIQ

Mostly agreed satisfied
63.6%
Strongly agreed satisfied
9.1%
Participants did not plan to switch to CIQ

Safety

TBR (<70 and <54 mg/dL)

Significantly lower with CIQ than AAPS

Original publication

Comparison of Control‐IQ and open‐source AndroidAPS automated insulin delivery systems in adults with type 1 diabetes: The CODIAC study. Diabetes Obes Metab. Published 25 September 2023. doi:10.1111/dom.15289

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.