Comparison of Control‐IQ and open‐source AndroidAPS automated insulin delivery systems in adults with type 1 diabetes: The CODIAC study
Authors' conclusion
The CODIAC study is the first prospective study investigating the switch between open-source and commercially available AID systems. CIQ and AAPS were comparable in achieving TIR. However, hypoglycaemia was significantly lower with CIQ.
Study context
- Population
- Adults with T1D who had been using AAPS by their own decision
- Participants
- 25 adults
- Exposure
- Control-IQ (CIQ) vs AAPS
- Outcome
- Change in % TIR (70-80 mg/dL as printed)
- Follow-up
- 3 months
Methodological detailsopen-label, sequential switch
- Open-label
- Sequential switch
Main finding
As reported in the abstract
TIR
P = 0.12
Observational data: associations, not effects.
Further findings
Mean sensor glucose · no difference
P = 0.21
| Outcome | CIQ | AAPS | P value |
|---|---|---|---|
| HbA1cNo difference | 6.3% ± 2.1% | 6.4% ± 3.1% | P = 0.59 |
TAR (>180 and >250 mg/dL)
- No differences between CIQ and AAPS
Satisfaction with CIQ
- Mostly agreed satisfied
- 63.6%
- Strongly agreed satisfied
- 9.1%
- Participants did not plan to switch to CIQ
Safety
TBR (<70 and <54 mg/dL)
- Significantly lower with CIQ than AAPS
Original publication
Comparison of Control‐IQ and open‐source AndroidAPS automated insulin delivery systems in adults with type 1 diabetes: The CODIAC study. Diabetes Obes Metab. Published 25 September 2023. doi:10. 1111/ dom. 15289
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