Type 1 diabetes

Reproducibility of plasma glucose responses to moderate‐intensity exercise in individuals with type 1 diabetes

Diabet MedPublished Pilot study

Authors' conclusion

Within-person plasma glucose responses to moderate-intensity exercise may be reproducible under fasting and basal insulin conditions and similar pre-exercise plasma glucose levels. This finding may assist the design of future studies investigating both the reproducibility of glycaemic responses to exercise and blood glucose management for individuals with type 1 diabetes.

Study context

Population
Young individuals with T1D; moderate-intensity morning exercise after overnight fasting under basal insulin conditions
Participants
8 individuals
Outcome
Within-person SD (SDw) in plasma glucose response, using the two visits per participant most closely matched by pre-exercise plasma glucose
Follow-up
During and 1 h after exercise
Methodological detailsrepeated-measures, three separate exercise days, 40 min moderate-intensity exercise at 60% V̇O2 peak on three separate days
  • Repeated-measures
  • Three separate exercise days
  • 40 min moderate-intensity exercise at 60% V̇O2 peak on three separate days

Main finding

As reported in the abstract

Within-person variability (SDw) of plasma glucose change
SDw of plasma glucose change during exercise
0.5 mmol (95% CI 0.2, 0.8)
SDw of plasma glucose change during recovery
0.8 mmoL/L (95% CI 0.4, 1.3)
Mean (±SD) change in plasma glucose during exercise
−1.8 ± 1.1 mmoL/L
Mean (±SD) change in plasma glucose during recovery
−0.6 ± 1.0 mmoL/L
Median intra-individual difference in plasma glucose change during exercise [IQR 0.1, 0.7]
0.3 mmoL/L
Median intra-individual difference in plasma glucose change during recovery [IQR 0.4, 1.0]
0.8 mmoL/L

Original publication

Reproducibility of plasma glucose responses to moderate‐intensity exercise in individuals with type 1 diabetes. Diabet Med. Published 16 November 2022. doi:10.1111/dme.15000

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