Relative handgrip strength correlates inversely with increased body fat, inflammatory markers and increased serum lipids in young, healthy adults – The LBA study

Diabetes Res Clin PractPublished Cross-sectional study

Authors' conclusion

RelHGS correlates with components of the MetS even in young, healthy populations. It is a better predictor of MetS components than absHGS. As a cheap and easy to use biomarker, relHGS holds merit as a screening tool for metabolic dysfunction even in preclinical contexts.

Study context

Population
Young, healthy adults aged 18–26 (LBA study)577 women
Participants
834 participants
Exposure
Absolute vs relative handgrip strength as predictors of metabolic syndrome (MetS) components
Outcome
Association of handgrip strength (HGS) with surrogate endpoints of MetS: waist circumference, HDL, fasting glucose, fasting insulin, TG, systolic and diastolic BP

Main finding

As reported in the abstract

Association of HGS with MetS surrogate endpoints (multivariable linear regression)
  • AbsHGS and relative HGS (relHGS) were each associated with several surrogate endpoints of MetS
  • RelHGS significantly associated with more variables — all except fasting glucose and diastolic blood pressure (BP)

Observational data: associations, not effects.

Original publication

Relative handgrip strength correlates inversely with increased body fat, inflammatory markers and increased serum lipids in young, healthy adults – The LBA study. Diabetes Res Clin Pract. Published 15 December 2023. doi:10.1016/j.diabres.2023.111057

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