Incidence and trends of type 1 diabetes before and after 2000 in the Western Pacific Region: A systematic review and meta-analysis
Authors' conclusion
T1DM incidence in the WPR is generally increasing, varying by age, sex, time and country. Results increase understanding of regional T1DM incidence and inform research and healthcare strategies.
Study context
- Population
- Population-based studies of T1D incidence, mostly in youth, in 11 Western Pacific Region countries, published 1973–201745 studies
- Outcome
- Mean annual T1D incidence/100,000 person years
- Follow-up
- After 2000
Methodological detailssubgroup analyses by time and by region
- Subgroup analyses by time and by region
Pooled result
As reported in the abstract
Mean annual T1D incidence/100,000 person years, aged 0-14 years
Lowest: Fiji
0.9
95 % CI, 0.6–1.3
Highest: Australia
23.2
95 % CI, 21.3–25.2
Further pooled results
Mean annual increase in incidence over time
- Australia (1990-2002)
- 2.8 %
- Shanghai (1997-2011)
- 14.2 %
- China: largest increase, over 30-years
- 2.7-fold
- Thailand, over 15-years
- 2-fold
Incidence by age and sex
- Most studies documented increasing incidence with age; only two studies included people aged ≥ 20 years
- Many, but not all studies reported significantly higher T1D incidence in females vs males
Original publication
Incidence and trends of type 1 diabetes before and after 2000 in the Western Pacific Region: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 15 December 2023. doi:10.
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