Relationship between stress hyperglycemia ratio and acute kidney injury in patients with congestive heart failure

Cardiovasc DiabetolPublished Cohort study

Authors' conclusion

Our study reveals a U-shaped relationship between SHR and AKI in patients with CHF. Notably, we identified an inflection point at an SHR value of 0.98, signifying a critical threshold for evaluating AKI in this population.

Study context

Population
Patients with congestive heart failure (CHF)
Participants
8,268 patients
Exposure
Stress hyperglycemia ratio (SHR) and in-hospital acute kidney injury (AKI)
Outcome
Incidence of AKI during hospitalization
Follow-up
During hospitalization

Main finding

As reported in the abstract

In-hospital AKI

AKI incidence in cohort

5,221

63.1%

U-shaped association between SHR and AKI after adjustment; inflection point

0.98

SHR >0.98: OR for AKI per SD increase

1.32

95% CI 1.22 to 1.46

Observational data: associations, not effects.

Original publication

Relationship between stress hyperglycemia ratio and acute kidney injury in patients with congestive heart failure. Cardiovasc Diabetol. Published 13 January 2024. doi:10.1186/s12933-023-02105-x

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