Type 2 & other diabetes

Relationship between intra-individual variability in nutrition-related lifestyle behaviors and blood glucose outcomes under free-living conditions in adults without type 2 diabetes

Diabetes Res Clin PractPublished Observational study

Authors' conclusion

Intra-individual variations in nutrition-related lifestyle behaviors, especially morning and evening body weight, and food intake, were associated with mean blood glucose levels, and a long sedentary time and total sleep time were associated with glucose variability. Earlier dinner times and shorter eating windows per day resulted in better glucose control.

Study context

Population
Adults without T2D
Participants
104 adults
Outcome
Relationship between intra-individual day-to-day variability in nutrition-related lifestyle behaviors (meal timing, eating window, food intake, movement behaviors, sleep, body weight) and glycemic outcomes
Follow-up
7 days
Methodological detailsfree-living conditions, 7-day measurement period, linear mixed-effects model, Food intake by mobile health app; movement and sleep by tri-axial accelerometer; meal timing from daily life record; continuous glucose monitoring
  • Free-living conditions
  • 7-day measurement period
  • Linear mixed-effects model
  • Food intake by mobile health app; movement and sleep by tri-axial accelerometer; meal timing from daily life record; continuous glucose monitoring

Main finding

As reported in the abstract

Glucose outcomes:
  • Mean
  • SD
  • Maximum blood glucose
Dinner time positively associated with mean blood glucose
p = 0.003
Eating window positively associated with mean blood glucose
p = 0.001
Dinner time and eating window positively associated with blood glucose SD
both at p < 0.001
Dinner time and eating window positively associated with maximum blood glucose
both at p < 0.001
Breakfast time negatively associated with glucose outcomes
p < 0.01
Sedentary time positively associated with blood glucose SD
p = 0.040
Total sleep time negatively associated with blood glucose SD
p = 0.035
Total sleep time negatively associated with maximum blood glucose
p = 0.032
Total daily energy intake positively associated with mean blood glucose
p = 0.001
Carbohydrate intake positively associated with mean blood glucose
p < 0.001
Body weight positively associated with mean blood glucose
p < 0.05

Observational data: associations, not effects.

Original publication

Relationship between intra-individual variability in nutrition-related lifestyle behaviors and blood glucose outcomes under free-living conditions in adults without type 2 diabetes. Diabetes Res Clin Pract. Published 21 December 2022. doi:10.1016/j.diabres.2022.110231

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