Relationship Between Extracellular Water to Total Body Water Ratio and Severe Diabetic Retinopathy in Type 2 Diabetes
Authors' conclusion
In patients with T2D younger than 60 years, the ET ratio may be a useful indicator for identifying severe DR.
Study context
- Population
- Adults with T2D, Department of Endocrinology, Metabolism, and Diabetes, Kyushu University Hospital
- Participants
- 205 adults
- Exposure
- Proliferative DR (PDR) vs non-PDR
- non-PDRn = 161reference
- PDRn = 44
- Outcome
- Relationship between severe DR and extracellular water to total body water ratio (ET ratio), measured by bioelectrical impedance analysis
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
ET ratio
- On multivariate logistic regression, ET ratio significantly associated with PDR, independent of known risk factors for diabetic retinopathy (DR) progression
- PDR vs non-PDR: P < 0.0001
Observational data: associations, not effects.
Further findings
ET ratio and PDR, subgroup age <60 years
- Significant association between ET ratio and PDR on multivariate logistic regression, independent of known risk factors for DR progression
ET ratio and PDR, subgroup age ≥60 years
- Only urinary albumin to creatinine ratio (UACR) significantly associated with PDR in a model using UACR and ET ratio
Original publication
Relationship Between Extracellular Water to Total Body Water Ratio and Severe Diabetic Retinopathy in Type 2 Diabetes. J Clin Endocrinol Metab. Published 1 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →